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Biossance Growth Factor Firming Anti-Aging Moisturizer with Peptides, Collagen + Squalane

This moisturizer aims to visibly firm skin and improve the appearance of fine lines and bounce. It utilizes a biomimetic growth factor, peptides, and encapsulated vegan collagen.

Sephora price

$64.00

Price matters most when you are trying to learn whether this lane belongs in your routine without turning the test into a luxury gamble.

Sephora reviews

4.7 / 5

About 277 reviews on the current Sephora source, so there is real volume behind the reputation.

Shoppers keep mentioning

Clean + Planet AwareAnti-AgingPeptideCollagenLoss of firmnessCruelty-Free

These are the shopper themes that keep showing up around this listing and shape why people open it in the first place.

Glass take

4.6 / 5 overall fit

A rich, firming moisturizer that targets fine lines and loss of elasticity with peptides, collagen, and squalane.

Biossance Growth Factor Firming Anti-Aging Moisturizer with Peptides, Collagen + Squalane

Sephora snapshot refreshed April 23, 2026

Price, rating, review count, and source status come from Sephora. Glass adds the routine fit, overlap risk, and what to compare next.

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What Sephora says

What this product is supposed to do

This moisturizer visibly firms skin with biomimetic growth factor, a plant-based peptide that improves the look of laxity, fine lines, and bounce.

NormalDryCombinationOilyAnti-agingFine Lines and WrinklesLoss of Firmness and Elasticity

Start with your cleanser. Next, apply eye and face treatments.

Finally, use your Growth Factor Firming Moisturizer on face and neck (avoiding eye area).

For daytime, SPF should be your final step. Use day and night.

What Glass adds

What actually matters before you buy it

A solid choice for those looking to address signs of aging, particularly loss of firmness and fine lines. The combination of peptides, collagen, and squalane offers a multi-pronged approach to skin rejuvenation.

Firming and plumping

Many users noted a noticeable improvement in skin's firmness and a plumper appearance after consistent use.

Hydration boost

The squalane and other hydrating ingredients provide lasting moisture without greasiness.

Best for

When this is a smart buy

  • Mature skin
  • Dry or combination skin
  • Those concerned with loss of firmness

Skip if

When this is the wrong lane

  • You have very oily skin and prefer lightweight formulas
  • You are sensitive to peptides or collagen ingredients

Routine fit

Where this fits in your routine

Apply this moisturizer after your serums and treatments, both in the morning and at night. For daytime use, always finish with SPF.

Why it works

Where it earns the slot and where it does not

The useful question is not whether this product is good in a vacuum. It is whether it makes your routine easier to run or just adds one more bottle with a familiar ingredient on it.

What it actually does well

  • Addresses multiple signs of aging
  • Contains beneficial peptides and collagen
  • Hydrating formula with squalane

Where it starts to feel redundant

  • Higher price point
  • May be too rich for very oily skin types

Routine fit

Where it belongs in the stack

Morning and Night

This moisturizer is suitable for both morning and evening application as the final step in your skincare routine before SPF (for daytime).

Glass rating

How this formula scores in real life

4.6/ 5 overall

A rich, firming moisturizer that targets fine lines and loss of elasticity with peptides, collagen, and squalane.

Texture

4.5 / 5

Creamy and hydrating, it absorbs well without feeling heavy.

Efficacy

4.7 / 5

Users report visible improvements in firmness and a reduction in the appearance of fine lines.

Full ingredient breakdown

Every ingredient, what it does, and whether I care

Solvent

Water/Aqua/Eau

Badness

0.0 / 10

The base for most cosmetic formulations.

Usually helps with

Hydration

Watch for

Humectant

Glycerin

Badness

0.0 / 10

Attracts water to the skin, helping to keep it hydrated and soft.

Usually helps with

Hydration

Watch for

Emollient

Vitis Vinifera (Grape) Seed Oil

Badness

1.0 / 10

A lightweight oil rich in antioxidants, known for its moisturizing properties.

Usually helps with

Moisturizing, antioxidant support

Watch for

Humectant

Propanediol

Badness

0.0 / 10

A solvent and humectant that can improve the penetration of other ingredients.

Usually helps with

Hydration, ingredient delivery

Watch for

Emollient

Squalane*

Badness

0.0 / 10

Mimics the skin's natural oils, providing excellent hydration and improving suppleness without feeling greasy.

Usually helps with

Hydration, barrier support

Watch for

Emollient

Cetearyl Alcohol

Badness

0.0 / 10

A fatty alcohol that helps to soften and smooth the skin, also acting as an emulsifier.

Usually helps with

Emollience, texture enhancement

Watch for

Thickener

Sodium Polyacrylate

Badness

0.0 / 10

Used to thicken formulations and improve texture.

Usually helps with

Texture

Watch for

Active

Saccharomyces Ferment Filtrate

Badness

2.0 / 10

A fermented ingredient that can offer antioxidant and skin-conditioning benefits.

Usually helps with

Skin conditioning

Watch for

Humectant

Butylene Glycol

Badness

0.0 / 10

A common humectant and solvent that helps ingredients penetrate the skin.

Usually helps with

Hydration, ingredient delivery

Watch for

Preservative

Phenoxyethanol

Badness

2.0 / 10

A common preservative used to prevent microbial growth in cosmetic products.

Usually helps with

Preservation

Watch for

Can be irritating for some sensitive skin types

Emollient

Undecane

Badness

0.0 / 10

A light emollient that provides a smooth feel on the skin.

Usually helps with

Emollience

Watch for

Emollient

Capryloyl Glycerin/Sebacic Acid Copolymer

Badness

0.0 / 10

A conditioning agent that helps to soften and smooth the skin.

Usually helps with

Emollience

Watch for

Emollient

Diheptyl Succinate

Badness

0.0 / 10

A plant-derived emollient that helps to condition and soften the skin.

Usually helps with

Emollience

Watch for

Emollient

Tridecane

Badness

0.0 / 10

A light emollient that provides a smooth feel on the skin.

Usually helps with

Emollience

Watch for

Antioxidant

Tocopherol

Badness

1.0 / 10

A form of Vitamin E, known for its antioxidant properties that help protect the skin from environmental damage.

Usually helps with

Antioxidant protection

Watch for

Preservative

Ethylhexylglycerin

Badness

1.0 / 10

A skin-conditioning agent and preservative booster.

Usually helps with

Preservation, skin conditioning

Watch for

Humectant

Sodium Pca

Badness

0.0 / 10

A component of the skin's natural moisturizing factor, it helps attract and retain moisture.

Usually helps with

Hydration

Watch for

Humectant

Sodium Lactate

Badness

0.0 / 10

A salt of lactic acid, it's a humectant that helps to hydrate the skin.

Usually helps with

Hydration

Watch for

Humectant

Hydrolyzed Sodium Hyaluronate

Badness

0.0 / 10

A smaller molecular weight form of hyaluronic acid, capable of penetrating deeper into the skin for hydration.

Usually helps with

Deep hydration

Watch for

Chelating Agent

Sodium Gluconate

Badness

0.0 / 10

A chelating agent that helps to improve the stability and efficacy of preservatives.

Usually helps with

Formulation stability

Watch for

Amino Acid

Arginine

Badness

0.0 / 10

An amino acid that helps to moisturize and condition the skin.

Usually helps with

Moisturizing, skin conditioning

Watch for

Amino Acid

Aspartic Acid

Badness

0.0 / 10

An amino acid that plays a role in skin conditioning.

Usually helps with

Skin conditioning

Watch for

Humectant

Pca

Badness

0.0 / 10

Pyrrolidone Carboxylic Acid, a component of the skin's natural moisturizing factor (NMF).

Usually helps with

Hydration

Watch for

Preservative

Sodium Benzoate

Badness

2.0 / 10

A common preservative that helps prevent the growth of bacteria and fungi.

Usually helps with

Preservation

Watch for

Can cause skin reactions in sensitive individuals, especially when combined with acidic ingredients

Preservative

Potassium Sorbate

Badness

2.0 / 10

A preservative used to inhibit the growth of mold, yeast, and bacteria.

Usually helps with

Preservation

Watch for

Thickener

Algin

Badness

0.0 / 10

A polysaccharide derived from seaweed, used as a thickening and stabilizing agent.

Usually helps with

Texture, stabilization

Watch for

Amino Acid

Glycine

Badness

0.0 / 10

An amino acid that helps to moisturize and condition the skin.

Usually helps with

Moisturizing, skin conditioning

Watch for

Amino Acid

Alanine

Badness

0.0 / 10

An amino acid that helps to moisturize and condition the skin.

Usually helps with

Moisturizing, skin conditioning

Watch for

Amino Acid

Serine

Badness

0.0 / 10

An amino acid that helps to moisturize and condition the skin.

Usually helps with

Moisturizing, skin conditioning

Watch for

Humectant

Sodium Hyaluronate

Badness

0.0 / 10

The salt form of hyaluronic acid, it attracts and holds moisture in the skin.

Usually helps with

Hydration

Watch for

Amino Acid

Valine

Badness

0.0 / 10

An amino acid that helps to moisturize and condition the skin.

Usually helps with

Moisturizing, skin conditioning

Watch for

Amino Acid

Isoleucine

Badness

0.0 / 10

An amino acid that helps to moisturize and condition the skin.

Usually helps with

Moisturizing, skin conditioning

Watch for

Amino Acid

Proline

Badness

0.0 / 10

An amino acid that plays a role in skin structure and hydration.

Usually helps with

Skin conditioning, hydration

Watch for

Active

Pseudostellaria Heterophylla Extract

Badness

2.0 / 10

A botanical extract that may offer antioxidant and skin-conditioning benefits.

Usually helps with

Skin conditioning

Watch for

Amino Acid

Threonine

Badness

0.0 / 10

An amino acid that helps to moisturize and condition the skin.

Usually helps with

Moisturizing, skin conditioning

Watch for

Emollient

Caprylyl Glycol

Badness

1.0 / 10

A skin-conditioning agent and preservative booster with antimicrobial properties.

Usually helps with

Skin conditioning, preservation

Watch for

Humectant

1,2-Hexanediol

Badness

0.0 / 10

A solvent and humectant that also has preservative-boosting properties.

Usually helps with

Hydration, preservation

Watch for

Active

Beta-Glucan

Badness

1.0 / 10

A polysaccharide known for its soothing, moisturizing, and skin-restoring properties.

Usually helps with

Soothing, hydration, barrier support

Watch for

Mineral

Calcium Citrate

Badness

0.0 / 10

A mineral salt that can act as a stabilizer or buffering agent.

Usually helps with

Formulation stability

Watch for

Active

Collagen

Badness

2.0 / 10

A structural protein that helps maintain skin's firmness and elasticity. When applied topically, it acts as a humectant and can help improve skin hydration.

Usually helps with

Firmness, hydration

Watch for

Larger molecules may sit on the skin's surface

Carbohydrate

Mannose

Badness

0.0 / 10

A simple sugar that can contribute to skin hydration and conditioning.

Usually helps with

Hydration, skin conditioning

Watch for

Amino Acid

Histidine

Badness

0.0 / 10

An amino acid that helps to moisturize and condition the skin.

Usually helps with

Moisturizing, skin conditioning

Watch for

Amino Acid

Phenylalanine

Badness

0.0 / 10

An amino acid that helps to moisturize and condition the skin.

Usually helps with

Moisturizing, skin conditioning

Watch for

pH Adjuster

Sodium Hydroxide

Badness

0.0 / 10

Used to adjust the pH of cosmetic formulations to ensure stability and efficacy.

Usually helps with

Formulation stability

Watch for

Can be irritating in high concentrations

Carbohydrate

Glucose

Badness

0.0 / 10

A simple sugar that can act as a humectant and skin conditioner.

Usually helps with

Hydration, skin conditioning

Watch for

Active

Hexapeptide-9

Badness

1.0 / 10

A peptide that can help improve the appearance of fine lines and wrinkles by supporting skin's natural collagen production.

Usually helps with

Anti-aging, wrinkle reduction

Watch for

Active

Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76

Badness

1.0 / 10

A synthetic peptide designed to mimic growth factors, promoting skin's natural repair processes and improving firmness.

Usually helps with

Firming, anti-aging

Watch for

Compare before you buy

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FAQ

The fast answers people actually need

What are the key benefits of this moisturizer?

This moisturizer is designed to visibly firm skin, improve the appearance of fine lines and wrinkles, and enhance skin's bounce and hydration.

Is this moisturizer suitable for all skin types?

It is suitable for normal, dry, combination, and oily skin types. However, those with very oily skin might prefer a lighter formula.

How does the growth factor in this product work?

The biomimetic growth factor in this formula is designed to mimic the skin's natural growth factors, helping to restore the look of youthful, collagen-rich skin and improve laxity.