Dr. Dennis Gross SkincareskincareTreat step

Dr. Dennis Gross Skincare Advanced Retinol + Ferulic Overnight Wrinkle Treatment

This overnight treatment combines retinol with ferulic acid to deliver potent anti-aging benefits while minimizing irritation. It aims to visibly firm the skin, reduce the appearance of wrinkles, and improve overall texture and hydration.

Sephora price

$89.00

Price matters most when you are trying to learn whether this lane belongs in your routine without turning the test into a luxury gamble.

Sephora reviews

4.5 / 5

About 284 reviews on the current Sephora source, so there is real volume behind the reputation.

Shoppers keep mentioning

HydratingBest for Dry SkinVeganGood for: Dark spotsGood for: Loss of firmnessGood for: DrynessRetinol: A vitamin A derivative that supports collagen production while visibly reversing signs of photo-aging, improving fine lines and wrinkles, addressing UV-induced free-radical damage, reducing blemish-causing sebum, and fading dark spots. Dr. Dennis Gross Skincare™ is a dermatologist-founded brand driven by clinical results. With every product we take a research-backed approach and formulate with pharmaceutical-grade active ingredients to ensure superior results, without irritation. Dr. Gross is an unwavering advocate for his patients, consumers, and humanity, bound by the Hippocratic Oath to do no harm. His mission – and ours–is to improve your skin health, how it looks, but most importantly how it makes you feel. We are cruelty-free, vegan, paraben-free, phthalate-free, and sulfate-free. Our #1 priority is to ensure efficacy without ever compromising safety.Fine Lines and WrinklesDrynessand Loss of Firmness and Elasticity

These are the shopper themes that keep showing up around this listing and shape why people open it in the first place.

Glass take

4.5 / 5 overall fit

A solid retinol treatment for those looking for anti-aging benefits without the typical irritation. It's particularly well-suited for dry skin types and those concerned with fine lines, wrinkles, and loss of firmness.

Dr. Dennis Gross Skincare Advanced Retinol + Ferulic Overnight Wrinkle Treatment

Sephora snapshot refreshed April 23, 2026

Price, rating, review count, and source status come from Sephora. Glass adds the routine fit, overlap risk, and what to compare next.

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What Sephora says

What this product is supposed to do

A hydrating, irritation-free, overnight retinol treatment that visibly firms and reduces the look of wrinkles.

NormalDryCombinationand OilyFine Lines and WrinklesDrynessand Loss of Firmness and Elasticity

For PM use.

Massage two to three pumps into clean, dry skin nightly—and remember your neck and décolleté.

For optimal results, apply after your Dr. Dennis Gross Skincare® peel and follow with a moisturizer if needed.

For stubborn blemish concerns, add Advanced Retinol + Ferulic Overnight Texture Renewal Peel (sold separately) to smooth and resurface skin.

What Glass adds

What actually matters before you buy it

This is a well-formulated retinol treatment that balances efficacy with a gentler approach. It's a good option for those new to retinol or those with drier skin who want to address signs of aging.

Visible reduction in wrinkles

Many users report a noticeable softening of fine lines and wrinkles after consistent use.

Improved skin texture and firmness

The combination of ingredients helps to improve skin's overall smoothness and elasticity.

Gentle yet effective

Users appreciate that it delivers results without causing excessive dryness or redness.

Best for

When this is a smart buy

  • Dry or mature skin
  • First-time retinol users
  • Those concerned with fine lines and wrinkles
  • People seeking a hydrating anti-aging treatment

Skip if

When this is the wrong lane

  • You have very oily skin and are only looking for oil control
  • You are already using multiple strong actives in your routine
  • You have a compromised skin barrier and need to focus on repair first

Routine Fit

Where this fits in your routine

Apply this treatment at night after cleansing and any exfoliating steps (like a Dr. Dennis Gross peel). If your skin feels dry, follow with a moisturizer. Remember to extend application to your neck and décolleté for comprehensive anti-aging benefits.

Key Ingredients Explained

The science behind the glow

Retinol is the star, working to accelerate cell turnover and boost collagen for smoother, firmer skin. Ferulic acid is a potent antioxidant that enhances retinol's stability and effectiveness while protecting against environmental damage. Niacinamide helps to improve skin barrier function and reduce redness, while hyaluronic acid provides essential hydration.

Why it works

Where it earns the slot and where it does not

The useful question is not whether this product is good in a vacuum. It is whether it makes your routine easier to run or just adds one more bottle with a familiar ingredient on it.

What it actually does well

  • Combines retinol and ferulic acid
  • Hydrating formula
  • Minimizes irritation
  • Addresses multiple signs of aging
  • Suitable for neck and décolleté

Where it starts to feel redundant

  • Higher price point
  • May not be potent enough for advanced retinol users
  • Requires consistent use for best results

Routine fit

Where it belongs in the stack

Nighttime Treatment

This product is designed for use in your evening skincare routine to work with your skin's natural overnight repair cycle.

Glass rating

How this formula scores in real life

4.5/ 5 overall

A solid retinol treatment for those looking for anti-aging benefits without the typical irritation. It's particularly well-suited for dry skin types and those concerned with fine lines, wrinkles, and loss of firmness.

Retinol Efficacy

4.6 / 5

Effectively targets wrinkles and firmness with a good balance of actives.

Hydration

4.4 / 5

Provides noticeable hydration, making it suitable for drier skin types.

Irritation Potential

4.3 / 5

Generally well-tolerated, but sensitive skin should still introduce it slowly.

Full ingredient breakdown

Every ingredient, what it does, and whether I care

Solvent

Water/Aqua/Eau

Badness

0.0 / 10

The base for many skincare formulations.

Usually helps with

Hydration

Watch for

Active

Niacinamide

Badness

2.0 / 10

A versatile ingredient that helps improve skin barrier function, reduce inflammation, and minimize the appearance of pores and fine lines.

Usually helps with

Redness, pores, barrier support, uneven tone

Watch for

Can sometimes cause flushing in sensitive individuals.

Humectant

Propanediol

Badness

0.0 / 10

A skin-conditioning agent that helps to attract and retain moisture.

Usually helps with

Hydration

Watch for

Emollient

Caprylic/Capric Triglyceride

Badness

0.0 / 10

A skin-conditioning agent derived from coconut oil and glycerin that helps to replenish the skin's surface.

Usually helps with

Soothing, softening

Watch for

Humectant

Glycerin

Badness

0.0 / 10

A common and effective humectant that draws water into the skin, keeping it hydrated and supple.

Usually helps with

Hydration, barrier support

Watch for

Active

Retinol

Badness

3.0 / 10

A derivative of Vitamin A that is a gold standard for anti-aging. It accelerates cell turnover, boosts collagen production, and helps to reduce the appearance of wrinkles, fine lines, and improve skin texture and tone.

Usually helps with

Anti-aging, wrinkles, texture, tone, acne

Watch for

Can cause irritation, dryness, and sun sensitivity, especially when first starting. Always use with SPF during the day.

Active

Bakuchiol

Badness

1.0 / 10

A plant-derived ingredient often considered a natural alternative to retinol. It offers similar anti-aging benefits like reducing the appearance of fine lines and improving skin texture, often with less irritation.

Usually helps with

Anti-aging, fine lines, texture, sensitive skin

Watch for

Antioxidant

Nephelium Lappaceum Leaf Extract

Badness

1.0 / 10

An extract from rambutan leaves, rich in antioxidants that help protect the skin from environmental stressors.

Usually helps with

Antioxidant protection

Watch for

Antioxidant

Ferulic Acid

Badness

1.0 / 10

A powerful antioxidant that helps to protect skin from environmental damage and enhances the stability and efficacy of other active ingredients like retinol.

Usually helps with

Antioxidant protection, anti-aging

Watch for

Humectant

Sodium Hyaluronate

Badness

0.0 / 10

A salt form of hyaluronic acid that attracts and retains moisture, providing hydration and plumping the skin.

Usually helps with

Hydration, plumping

Watch for

Exfoliant

Lactic Acid

Badness

2.0 / 10

An Alpha Hydroxy Acid (AHA) that exfoliates the skin's surface, revealing brighter, smoother skin. It also has hydrating properties.

Usually helps with

Exfoliation, brightening, hydration

Watch for

Can increase sun sensitivity. May cause mild stinging.

Emollient

Linoleic Acid

Badness

0.0 / 10

An omega-6 fatty acid that is a component of the skin's natural barrier. It helps to maintain skin hydration and suppleness.

Usually helps with

Barrier support, hydration

Watch for

Emollient

Linolenic Acid

Badness

0.0 / 10

An omega-3 fatty acid that helps to support the skin barrier and reduce inflammation.

Usually helps with

Barrier support, anti-inflammatory

Watch for

Antioxidant

Silybum Marianum Extract

Badness

1.0 / 10

Milk thistle extract, known for its antioxidant and anti-inflammatory properties.

Usually helps with

Antioxidant protection, soothing

Watch for

Humectant

Saccharide Isomerate

Badness

0.0 / 10

A plant-derived ingredient that binds to skin cells and provides long-lasting hydration.

Usually helps with

Deep hydration

Watch for

Emollient

Phospholipids

Badness

0.0 / 10

Essential components of cell membranes that help to restore and maintain the skin's barrier function.

Usually helps with

Barrier repair, hydration

Watch for

Emollient

Oenothera Biennis (Evening Primrose) Flower Extract

Badness

1.0 / 10

Contains gamma-linolenic acid (GLA), which can help soothe and moisturize the skin.

Usually helps with

Soothing, moisturizing

Watch for

Skin-Conditioning Agent

Adenosine

Badness

1.0 / 10

A naturally occurring compound that can help improve the appearance of wrinkles by promoting skin's elasticity.

Usually helps with

Anti-aging, firmness

Watch for

Skin-Conditioning Agent

Evodia Rutaecarpa Fruit Extract

Badness

2.0 / 10

An extract from the Evodia fruit, known for its potential to improve skin radiance and texture.

Usually helps with

Radiance, texture

Watch for

Humectant

Sodium PCA

Badness

0.0 / 10

A component of the skin's Natural Moisturizing Factor (NMF), it helps to attract and bind moisture to the skin.

Usually helps with

Hydration

Watch for

Antioxidant

Camellia Sinensis Leaf Extract

Badness

1.0 / 10

Green tea extract, rich in antioxidants that help protect the skin from free radical damage.

Usually helps with

Antioxidant protection, soothing

Watch for

Chelating Agent

Phytic Acid

Badness

1.0 / 10

An antioxidant found in plant seeds that can help to gently exfoliate and brighten the skin.

Usually helps with

Brightening, gentle exfoliation

Watch for

Antioxidant

Tocopherol

Badness

1.0 / 10

A form of Vitamin E, it's an antioxidant that helps protect the skin from environmental damage and can also moisturize.

Usually helps with

Antioxidant protection, moisturizing

Watch for

Exfoliant

Glycolic Acid

Badness

3.0 / 10

An Alpha Hydroxy Acid (AHA) that effectively exfoliates the skin, revealing a brighter and smoother complexion. It can also help with fine lines and hyperpigmentation.

Usually helps with

Exfoliation, brightening, fine lines, hyperpigmentation

Watch for

Can cause stinging and increased sun sensitivity. Not recommended for very sensitive skin or compromised barriers.

Exfoliant

Mandelic Acid

Badness

2.0 / 10

An Alpha Hydroxy Acid (AHA) with a larger molecule size, making it gentler for exfoliation. It's particularly good for acne-prone and sensitive skin.

Usually helps with

Gentle exfoliation, acne, sensitive skin

Watch for

Can cause mild irritation or peeling.

Binder

Maltodextrin

Badness

0.0 / 10

A polysaccharide used as a binder and to improve the texture of formulations.

Usually helps with

Texture enhancement

Watch for

pH Adjuster

Sodium Hydroxide

Badness

0.0 / 10

Used to adjust the pH of the product to ensure stability and efficacy.

Usually helps with

Watch for

Can be irritating in high concentrations.

Emollient

Cetyl Alcohol

Badness

0.0 / 10

A fatty alcohol that acts as an emollient, helping to soften and smooth the skin.

Usually helps with

Softening, smoothing

Watch for

Film Former

PVM/MA Decadiene Crosspolymer

Badness

0.0 / 10

A synthetic polymer used to create a film on the skin, which can help with texture and product longevity.

Usually helps with

Texture

Watch for

Emollient

Behenyl Alcohol

Badness

0.0 / 10

A fatty alcohol that acts as an emollient and thickener, helping to condition the skin.

Usually helps with

Conditioning, thickening

Watch for

Emulsifier

Glyceryl Stearate SE

Badness

0.0 / 10

An emulsifier that helps to blend oil and water ingredients, creating a stable formulation.

Usually helps with

Emulsification

Watch for

Emulsifier

Arachidyl Glucoside

Badness

0.0 / 10

A non-ionic emulsifier derived from plant-based sources, used to create stable emulsions.

Usually helps with

Emulsification

Watch for

Emollient

Arachidyl Alcohol

Badness

0.0 / 10

A fatty alcohol that acts as an emollient and emulsifier, helping to soften and condition the skin.

Usually helps with

Emollient, emulsifying

Watch for

Preservative Booster

Ethylhexylglycerin

Badness

0.0 / 10

A preservative booster and skin-conditioning agent that also has antimicrobial properties.

Usually helps with

Preservation, skin conditioning

Watch for

Emulsifier

Oleth-10

Badness

1.0 / 10

An emulsifier that helps to mix oil and water ingredients. Can be derived from ethoxylated sources.

Usually helps with

Emulsification

Watch for

Emulsifier

PEG-40 Hydrogenated Castor Oil

Badness

1.0 / 10

A non-ionic emulsifier and surfactant used to solubilize oils and fragrances. Can be ethoxylated.

Usually helps with

Emulsification

Watch for

Antioxidant

Sodium Ascorbate

Badness

1.0 / 10

A stable salt form of Vitamin C, acting as an antioxidant to protect the skin from free radical damage.

Usually helps with

Antioxidant protection

Watch for

Antioxidant

Citrus Limon (Lemon) Peel Extract

Badness

2.0 / 10

Contains Vitamin C and antioxidants, but can also be phototoxic and irritating due to limonene and citral.

Usually helps with

Brightening, antioxidant

Watch for

Potential for photosensitivity and irritation.

Fragrance

Citrus Aurantium Bergamia (Bergamot) Fruit Extract

Badness

3.0 / 10

A fragrance ingredient derived from the bergamot orange. It can be phototoxic and a potential allergen.

Usually helps with

Fragrance

Watch for

Potential for photosensitivity, irritation, and allergic reactions.

Fragrance

Lavandula Angustifolia (Lavender) Flower/Leaf/Stem Extract

Badness

2.0 / 10

A botanical extract used for its fragrance and potential soothing properties. However, it can be a potential allergen for some.

Usually helps with

Fragrance, soothing

Watch for

Potential allergen for sensitive skin.

Preservative

Phenoxyethanol

Badness

2.0 / 10

A common preservative used to prevent microbial growth in cosmetic products. Can be irritating for some.

Usually helps with

Preservation

Watch for

Can cause skin irritation or allergic reactions in sensitive individuals.

Preservative

Sodium Benzoate

Badness

1.0 / 10

A preservative that helps prevent the growth of bacteria, yeast, and mold. Can cause irritation in sensitive individuals.

Usually helps with

Preservation

Watch for

Potential for irritation.

Preservative

Potassium Sorbate

Badness

1.0 / 10

A preservative used to inhibit the growth of mold, yeast, and fungi. Generally considered safe.

Usually helps with

Preservation

Watch for

Fragrance

Citrus Auranitum Bergamia (Bergamot) Fruit Extract

Badness

5.0 / 10

Included in the source ingredient list. Glass treats this as part of the supporting formula unless it overlaps with a known active, preservative, or fragrance flag.

Usually helps with

Formula completeness and routine context

Watch for

Personal sensitivity, especially if your skin is reactive or the ingredient overlaps with other products in your routine

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FAQ

The fast answers people actually need

Is this retinol treatment suitable for sensitive skin?

While formulated to be less irritating than traditional retinol, sensitive skin types should still introduce it slowly, perhaps starting with every other night, and monitor for any adverse reactions. The inclusion of bakuchiol and hydrating ingredients helps to mitigate potential irritation.

Can I use this with my exfoliating acids?

It's generally recommended to use this retinol treatment on alternate nights to your strong exfoliating acids (like glycolic or salicylic acid) to avoid over-exfoliation and irritation. However, the product itself contains Lactic, Glycolic, and Mandelic acids, so it's best to follow the brand's recommendation of applying after their peel if you use it, or use it on nights you are not using other strong exfoliants.

How long will it take to see results?

Results can vary, but many users start to see improvements in skin texture and hydration within a few weeks. More significant changes in fine lines, wrinkles, and firmness typically become noticeable after 8-12 weeks of consistent use.