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Rejuran Nutritive Cream c-PDRN 0.2% Nourishing Moisturizer for Visible Firmness & Barrier Support

This cream delivers a substantial dose of hydration and nutrients, making it a go-to for skin that feels dry, tight, or is showing early signs of aging. The inclusion of c-PDRN aims to boost skin's natural renewal processes.

Sephora price

$54.00

Price matters most when you are trying to learn whether this lane belongs in your routine without turning the test into a luxury gamble.

Sephora reviews

4.6 / 5

About 96 reviews on the current Sephora source, so there is real volume behind the reputation.

Shoppers keep mentioning

RejuranVisible FirmnessBarrier Support

These are the shopper themes that keep showing up around this listing and shape why people open it in the first place.

Glass take

4.6 / 5 overall fit

A rich, nourishing moisturizer that effectively supports skin firmness and barrier function, ideal for dry and maturing skin types.

Rejuran Nutritive Cream c-PDRN 0.2% Nourishing Moisturizer for Visible Firmness & Barrier Support

Sephora snapshot refreshed April 23, 2026

Price, rating, review count, and source status come from Sephora. Glass adds the routine fit, overlap risk, and what to compare next.

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What Sephora says

What this product is supposed to do

A rich hydrating moisturizer that nourishes dry skin and visibly improves firmness and smoothness.

DrynessUneven TextureLoss of Firmness and Elasticity

After cleansing, toning, and ampoule, apply an appropriate amount evenly to the face and neck.

Gently massage until fully absorbed.

Use morning and evening as part of your daily skincare routine.

What Glass adds

What actually matters before you buy it

This is a solid moisturizer for anyone prioritizing barrier support and a smoother, firmer-feeling complexion. It's particularly well-suited for dry or mature skin, or for use in drier climates.

Best for

When this is a smart buy

  • Dry or dehydrated skin
  • Mature skin
  • Anyone seeking improved firmness and barrier support

Skip if

When this is the wrong lane

  • You have very oily skin and prefer a lightweight formula
  • You are sensitive to fragrance

Routine Fit

Where this fits in your routine

Apply this cream as the final step in your morning and evening skincare routine, after serums and treatments. Gently massage it into the skin until fully absorbed to lock in moisture and active ingredients.

Why it works

Where it earns the slot and where it does not

The useful question is not whether this product is good in a vacuum. It is whether it makes your routine easier to run or just adds one more bottle with a familiar ingredient on it.

What it actually does well

  • Deeply hydrating
  • Improves skin texture and firmness
  • Supports skin barrier health
  • Contains beneficial c-PDRN

Where it starts to feel redundant

  • Higher price point
  • Contains fragrance
  • May be too rich for very oily skin types

Routine fit

Where it belongs in the stack

Morning and Night

This moisturizer is designed for both AM and PM use. It provides essential hydration and barrier support throughout the day and helps skin recover overnight.

Glass rating

How this formula scores in real life

4.6/ 5 overall

A rich, nourishing moisturizer that effectively supports skin firmness and barrier function, ideal for dry and maturing skin types.

Full ingredient breakdown

Every ingredient, what it does, and whether I care

Solvent

Water

Badness

0.0 / 10

The base for most skincare formulations.

Usually helps with

Hydration

Watch for

Emollient

Simmondsia Chinensis (Jojoba) Seed Oil

Badness

0.0 / 10

Mimics skin's natural sebum, providing excellent moisturization without clogging pores.

Usually helps with

Dryness, balancing oil

Watch for

Emollient

Punica Granatum Seed Oil

Badness

1.0 / 10

Rich in antioxidants and fatty acids, it helps to nourish and protect the skin.

Usually helps with

Dryness, antioxidant support

Watch for

Emollient

Argania Spinosa Kernel Oil

Badness

0.0 / 10

Deeply moisturizing and rich in vitamin E, it helps improve skin elasticity.

Usually helps with

Dryness, firmness

Watch for

Emollient

Rosa Canina Fruit Oil

Badness

1.0 / 10

Contains essential fatty acids and antioxidants, aiding in skin repair and hydration.

Usually helps with

Dryness, barrier repair

Watch for

Emollient

Borago Officinalis Seed Oil

Badness

1.0 / 10

A source of gamma-linolenic acid (GLA), known for its anti-inflammatory and skin-soothing properties.

Usually helps with

Irritation, dryness

Watch for

Emollient

Butyrospermum Parkii (Shea) Butter

Badness

0.0 / 10

Provides intense moisture, softens skin, and has anti-inflammatory properties.

Usually helps with

Dryness, barrier support

Watch for

Emollient

Squalane

Badness

0.0 / 10

A highly stable and effective moisturizer that mimics skin's natural lipids, improving suppleness.

Usually helps with

Dryness, barrier support

Watch for

Emollient

Caprylic/Capric Triglyceride

Badness

0.0 / 10

A lightweight, non-greasy emollient derived from coconut oil and glycerin, used to replenish skin.

Usually helps with

Dryness, texture improvement

Watch for

Humectant

Glycerin

Badness

0.0 / 10

A classic humectant that draws water into the skin, keeping it hydrated and soft.

Usually helps with

Hydration

Watch for

Soothing Agent

Aloe Barbadensis Leaf Juice

Badness

0.0 / 10

Known for its hydrating, anti-inflammatory, and wound-healing properties.

Usually helps with

Irritation, hydration

Watch for

Emollient

Cetyl Alcohol

Badness

0.0 / 10

A fatty alcohol that softens and smooths skin, and helps to thicken formulations.

Usually helps with

Softening skin

Watch for

Emulsifier

Glyceryl Stearate

Badness

0.0 / 10

Helps to mix oil and water, and also acts as an emollient.

Usually helps with

Texture

Watch for

Humectant

Sodium Hyaluronate

Badness

0.0 / 10

The salt form of hyaluronic acid, it attracts and holds moisture in the skin.

Usually helps with

Hydration, plumping

Watch for

Emollient

Cetearyl Alcohol

Badness

0.0 / 10

A fatty alcohol that conditions and softens skin, and stabilizes emulsions.

Usually helps with

Softening skin

Watch for

Emollient

Dimethicone

Badness

1.0 / 10

A silicone that forms a protective barrier on the skin, preventing moisture loss and providing a smooth feel.

Usually helps with

Smoothing, moisture barrier

Watch for

Can feel heavy for some skin types

Antioxidant

Tocopheryl Acetate

Badness

1.0 / 10

A form of Vitamin E that protects skin from environmental damage.

Usually helps with

Antioxidant protection

Watch for

Soothing Agent

(-) alpha bisabolol

Badness

0.0 / 10

A derivative of chamomile, known for its anti-inflammatory and skin-calming properties.

Usually helps with

Irritation, redness

Watch for

Humectant

Panthenol

Badness

0.0 / 10

Pro-vitamin B5, it hydrates, soothes, and aids in skin barrier repair.

Usually helps with

Hydration, barrier repair

Watch for

Antioxidant

Citrus Aurantium Dulcis (Orange) Peel Extract

Badness

2.0 / 10

Contains antioxidants and can offer mild brightening benefits, but can also be a potential irritant for some.

Usually helps with

Antioxidant support

Watch for

Potential for photosensitivity or irritation in sensitive skin

Fragrance

Pelargonium Graveolens Flower/Leaf/Stem Extract

Badness

3.0 / 10

Adds a floral scent to the product.

Usually helps with

Scent

Watch for

Can be a potential irritant for sensitive skin

Soothing Agent

Cucumis Sativus (Cucumber) Seed Extract

Badness

0.0 / 10

Known for its cooling and soothing properties, helping to calm irritated skin.

Usually helps with

Soothing, hydration

Watch for

Preservative

Ethylhexylglycerin

Badness

1.0 / 10

A skin-conditioning agent that also has preservative properties, often used to boost the efficacy of other preservatives.

Usually helps with

Preservation

Watch for

Humectant

Caprylyl Glycol

Badness

0.0 / 10

A humectant that also helps to improve the texture and preservation of the product.

Usually helps with

Hydration, preservation

Watch for

Preservative

Phenoxyethanol

Badness

2.0 / 10

A common preservative used to prevent microbial growth in cosmetics.

Usually helps with

Preservation

Watch for

Can be irritating for some individuals

Active

Hydrolyzed DNA

Badness

1.0 / 10

The key ingredient c-PDRN, known for its regenerative and skin-firming properties.

Usually helps with

Firmness, barrier repair, texture

Watch for

Fragrance

Fragrance

Badness

5.0 / 10

Adds a scent to the product.

Usually helps with

Scent

Watch for

Can be a common cause of skin irritation and allergic reactions

Soothing Agent

Avena Sativa (Oat) Kernel Extract

Badness

0.0 / 10

Known for its anti-inflammatory and skin-soothing properties, helping to calm redness and irritation.

Usually helps with

Soothing, irritation

Watch for

Thickener

Carbomer

Badness

0.0 / 10

A thickening agent used to create gel-like textures and stabilize formulations.

Usually helps with

Texture

Watch for

Preservative

Sodium Benzoate

Badness

2.0 / 10

A common preservative that helps prevent the growth of bacteria and fungi.

Usually helps with

Preservation

Watch for

Can be irritating for some, especially in combination with acidic ingredients

Skin-Restoring

Adenosine

Badness

1.0 / 10

A beneficial ingredient known for its anti-wrinkle and skin-restoring properties.

Usually helps with

Firmness, anti-aging

Watch for

Soothing Agent

Glycyrrhiza Glabra (Licorice) Root Extract

Badness

1.0 / 10

Known for its anti-inflammatory and brightening properties, helping to calm skin and even tone.

Usually helps with

Soothing, brightening

Watch for

Compare before you buy

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FAQ

The fast answers people actually need

Is this moisturizer good for dry skin?

Yes, this is a rich, nourishing moisturizer that is particularly well-suited for dry and dehydrated skin types due to its emollient and hydrating ingredients.

What is c-PDRN?

c-PDRN is a patented ingredient derived from salmon DNA, known for its ability to promote skin regeneration, improve firmness, and support the skin barrier.

Can I use this if I have sensitive skin?

While it contains soothing ingredients like Aloe Vera and Licorice Root Extract, it also contains fragrance and some botanical extracts that could potentially irritate very sensitive skin. A patch test is recommended.

Rejuran Nutritive Cream c-PDRN 0.2% Review: Firmness and Barrier Support | Glass